Intermittent fasting (IF) has gained popularity as a dietary strategy not only for weight management but also for its potential health benefits, including its effects on inflammation. Understanding the hormonal changes induced by IF and how these changes influence inflammation can provide deeper insights into its potential therapeutic applications.

At its core, intermittent fasting involves alternating periods of eating and fasting. This dietary pattern can vary widely, from daily time-restricted feeding to alternate-day fasting or the 5:2 approach, where individuals eat normally for five days and restrict calories for two days. Regardless of the method, the underlying principle is the same: creating a cycle of feeding and fasting that triggers metabolic and hormonal shifts.

Hormonal Changes Induced by Intermittent Fasting

One of the most significant hormonal changes during intermittent fasting is the reduction in insulin levels. Insulin is a hormone produced by the pancreas that allows cells to absorb glucose from the bloodstream. During fasting, insulin levels drop, which facilitates fat burning and reduces fat storage. Lower insulin levels are associated with improved insu...